If you are coming by land just follow the instructions below.

We're only 15 minutes from Cape Coral and 50 minutes from Ft. Myers Airport.

By Land:

I-75
Exit #143 (Pine Island Rd).
Go west 23 miles through Cape Corral and Matlacha to Pine Island.
Turn left at Stringfellow Rd (4-way stop).
Stay on Stringfellow Rd 8 miles to the end.
Southernmost Inn is on the right at the very end of the island.
 

If you are coming by water simply follow the instructions below.

By Water:
Access from Pine Island Sound or Matlacha Pass.
Take mile marker 16 to the North and we are located at the entrance of the canal on the right.